BDBM50652973 CHEMBL5705847

SMILES CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(/C=C/c4cnc5[nH]ccc5c4OC)c3)cc2C(F)(F)F)CC1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50652973   

TargetTyrosine-protein kinase Lyn(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 30nMAssay Description:Inhibition of LYN (unknown origin) Lys1 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 41nMAssay Description:Inhibition of TAK1 (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetTyrosine-protein kinase ABL2(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 52nMAssay Description:Inhibition of ARG (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetTyrosine-protein kinase ABL1(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 52nMAssay Description:Inhibition of ABL (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetEphrin type-B receptor 4(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 54nMAssay Description:Inhibition of EphB4 (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetEphrin type-B receptor 2(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 75nMAssay Description:Inhibition of EphB2 (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetEphrin type-A receptor 2(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 77nMAssay Description:Inhibition of EphA2 (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetTyrosine-protein kinase CSK(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 81nMAssay Description:Inhibition of CSK (unknown origin) ACT labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 98nMAssay Description:Inhibition of MAP4K2 (unknown origin) Lys1 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 204nMAssay Description:Inhibition of SRC (unknown origin) Lys1 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase 14(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 238nMAssay Description:Inhibition of p38 alpha (unknown origin) by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase 20(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 469nMAssay Description:Inhibition of ZAK (unknown origin) Lys1 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of RAF1 (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 9.75E+3nMAssay Description:Inhibition of ZC1/HGK (unknown origin) Lys1 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetSerine/threonine-protein kinase B-raf(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BRAF (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase 8(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase 10(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase 9(Human)
Harvard Medical School

Curated by ChEMBL

LigandBDBM50652973(CHEMBL5705847)Copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK2 (unknown origin) Lys2 labeling site by KiNativ Profiling analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
10/13/2025
Entry Details
Copy BDB DOIPubMed
Copy reaction URL