BDBM50653011 CHEMBL5712050

SMILES CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(N[C@H](CCN5CCOCC5)CSc5ccccc5)c(S(=O)(=O)C(F)(F)Cl)c4)cc3)CC2)=C(c2ccc(Cl)cc2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50653011   

TargetApoptosis regulator Bcl-2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50653011(CHEMBL5712050)
Affinity DataKi:  0.0480nMAssay Description:Binding affinity to Bcl-2 (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50653011(CHEMBL5712050)
Affinity DataKi:  0.463nMAssay Description:Binding affinity to Bcl-xl (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50653011(CHEMBL5712050)
Affinity DataKi:  2nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50653011(CHEMBL5712050)
Affinity DataKi: >3.90E+3nMAssay Description:Binding affinity to MCL-1 (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed