BDBM50653104 CHEMBL5722987

SMILES CN(c1c(cccn1)CNc2ccnc(n2)Nc3ccc4c(c3)CC(=O)N4)S(=O)(=O)C

InChI Key InChIKey=BTIZXJFJJCRTBP-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50653104   

TargetProtein-tyrosine kinase 2-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653104BDBM50653104(CHEMBL5722987)
Affinity DataKi:  2.30nMAssay Description:Inhibition of full-length PYK2 (unknown origin) with C-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653104BDBM50653104(CHEMBL5722987)
Affinity DataKi:  4.10nMAssay Description:Inhibition of full-length FAK (unknown origin) with N-terminal NanoLuc-fusion expressed in HEK293T cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein-tyrosine kinase 2-beta(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653104BDBM50653104(CHEMBL5722987)
Affinity DataKd:  820nMAssay Description:Binding affinity to human recombinant PYK2 (amino acids 420-691) expressed in Escherichia coli, BL21 (DE3) assessed as equilibrium dissociation const...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed