BDBM50653463 CHEMBL6133963

SMILES O=c1c2ccncc2nc(Cl)n1-c1ccc(Cl)c(NS(=O)(=O)c2cc(F)ccc2F)c1

InChI Key InChIKey=OOHMCAHWXZLJEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50653463   

LigandChemical structure of BindingDB Monomer ID 50653463BDBM50653463(CHEMBL6133963)
Affinity DataIC50: 8.40nMAssay Description:Antagonist activity at calcium sensing receptor (unknown origin) by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Mus musculus)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653463BDBM50653463(CHEMBL6133963)
Affinity DataIC50: 165nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed