BDBM50653469 CHEMBL6133612

SMILES CS(=O)(=O)c1ccc2nc(Cl)n(-c3ccc(Cl)c(NS(=O)(=O)c4c(F)cccc4F)c3)c(=O)c2c1

InChI Key InChIKey=GHBVLILIUCLYKI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50653469   

LigandChemical structure of BindingDB Monomer ID 50653469BDBM50653469(CHEMBL6133612)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]-LSD from human 5-HT7 receptor after 1.5 hrs by cell based assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50653469BDBM50653469(CHEMBL6133612)
Affinity DataIC50: 0.800nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Mus musculus)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653469BDBM50653469(CHEMBL6133612)
Affinity DataIC50: 32nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Mus musculus)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653469BDBM50653469(CHEMBL6133612)
Affinity DataIC50: 32nMAssay Description:Positive allosteric modulation of mGlu5 receptor (unknown origin) assessed as increase in L-glutamate-induced calcium release after 60 mins by cell b...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed