BDBM50653743 CHEMBL6082972::US12605353, Compound 4

SMILES C#CC(=O)Nc1cc(OC)c(OC)cc1C(=O)OC

InChI Key InChIKey=RJZSMWCMFYBHTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50653743   

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50653743BDBM50653743(CHEMBL6082972 | US12605353, Compound 4)
Affinity DataIC50: 11.7nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase(Human)
Taipei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653743BDBM50653743(CHEMBL6082972 | US12605353, Compound 4)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed