BDBM50655301 CHEMBL6149971
SMILES CNC(=O)c1ccc(N2CCN(Cc3cc4c5c(cnn5[C@H](C)C(=O)N4)c3)CC2)c(C)n1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50655301
Affinity DataKd: <0.200nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 35nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 66nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 103nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 183nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 320nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 845nMAssay Description:Agonist activity at human PPARgamma incubated for 12 hrs by cell based Steady-Glo luciferase assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease by cell based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.00E+3nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.00E+3nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.00E+3nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5.00E+3nMAssay Description:Stabilization of SMURF1 (unknown origin) assessed as decrease in auto-ubiquitination by measuring increase in protein level by cell-based assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 9.88E+3nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells co-transfected with human RXR assessed as luciferase activity incubated for 2...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.26E+5nMAssay Description:Inhibition of HHAT in human HEK293a SHH+ cells assessed as inhibition SHH-YnPal tagging measured after 7 hrs by cell-based tagging assayMore data for this Ligand-Target Pair
Ligand Info