BDBM50655353 CHEMBL6147019

SMILES Cc1cc(F)cc(C)c1Oc1ccc(C(C)(C)O)cc1-c1cn(C)c(=O)c2cc(-c3[nH]c(C(C)C)nc3C)oc12

InChI Key InChIKey=AGWYRFVJWSGEKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50655353   

TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655353BDBM50655353(CHEMBL6147019)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD4 BD2 (348 to 464 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655353BDBM50655353(CHEMBL6147019)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST fused his tagged human BRD3 BD2 (307 to 419 residues) extracted from Escherichia coli BL21 (DE3) cells using biotinylate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655353BDBM50655353(CHEMBL6147019)
Affinity DataIC50: 2.03E+3nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) incubated for 24 hrs by cell based microplate analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed