BDBM50655485 CHEMBL6148535

SMILES O=C(Nc1ccc(-c2nc3cc(C(F)(F)F)ccc3[nH]2)cc1)c1cc(CNC(=O)C2(C(F)(F)F)CCC2)ccc1Cl

InChI Key InChIKey=ZEZQIUUYKKISDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50655485   

TargetProstaglandin E synthase(Human)
Gazi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655485BDBM50655485(CHEMBL6148535)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-beta induced PGE2 release preincubated for 15 mins followed by PGH2 addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed