BDBM50655840 CHEMBL6166085

SMILES CC[C@@H](c1cn(-c2ccc(C(=O)OC)cc2)nn1)n1cc(OC)c(-c2cc(Cl)ccc2-n2cc(Cl)nn2)cc1=O

InChI Key InChIKey=WQHWXGCEKKRZRH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50655840   

TargetCoagulation factor XI(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655840BDBM50655840(CHEMBL6166085)
Affinity DataIC50: 32nMAssay Description:Inhibition of human Factor XIa using Boc-Glu(OBzl)-Ala-Arg-AMC assessed as AMC release preincubated for 15 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655840BDBM50655840(CHEMBL6166085)
Affinity DataIC50: 643nMAssay Description:Inhibition of human PKa using H-Pro-Phe-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetCoagulation factor X(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655840BDBM50655840(CHEMBL6166085)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human Factor Xa using Boc-Ile-Glu-Gly-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProthrombin(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655840BDBM50655840(CHEMBL6166085)
Affinity DataIC50: 6.77E+4nMAssay Description:Inhibition of human thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetTrypsin(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655840BDBM50655840(CHEMBL6166085)
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibition of human trypsin using Boc-Ile-Glu-Gly-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed