BDBM50655852 CHEMBL6145552

SMILES COc1cn(Cc2cn(-c3cnn(C)c3)nn2)c(=O)cc1-c1cc(Cl)ccc1-n1cc(Cl)nn1

InChI Key InChIKey=FSSUJUGGGFTWJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50655852   

TargetCoagulation factor XI(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655852BDBM50655852(CHEMBL6145552)
Affinity DataIC50: 288nMAssay Description:Inhibition of human Factor XIa using Boc-Glu(OBzl)-Ala-Arg-AMC assessed as AMC release preincubated for 15 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Sichuan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50655852BDBM50655852(CHEMBL6145552)
Affinity DataIC50: 3.74E+3nMAssay Description:Inhibition of human PKa using H-Pro-Phe-Arg-AMC as substrate incubated for 15 mins by fluorescence reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed