BDBM50656023 CHEMBL1324227

SMILES N#Cc1ccc(N2C(=O)[C@@H]3C(C(=O)c4ccc5ccccc5n4)=NN[C@@H]3C2=O)cc1

InChI Key InChIKey=XZQXLMOGBXORHQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50656023   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656023BDBM50656023(CHEMBL1324227)
Affinity DataKi:  1.51E+4nMAssay Description:Mixed type inhibition of human his-tagged 15-LOX-2 expressed in Escherichia coli BL21 DE3 pLysS cells assessed as inhibition constant by lineweaver-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of Sao Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656023BDBM50656023(CHEMBL1324227)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human his-tagged 15-LOX-2 expressed in Escherichia coli BL21 DE3 pLysS cells using arachidonic acid as substrate preincubated for 2 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed