BDBM50656356 CHEMBL6147642

SMILES C[C@@H](Oc1nc2c(F)c(-c3cc(O)cc4ccccc34)c(CCC#N)cc2c2c1nc(CCC(=O)N(C)C)n2[C@H]1[C@H]2CN[C@@H]1C2)C1CCCN1C

InChI Key InChIKey=CFEPPJMLIGYTJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50656356   

TargetGTPase KRas(Human)
Incyte

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656356BDBM50656356(CHEMBL6147642)
Affinity DataIC50: 15nMAssay Description:Inhibition of bodipy-loaded KRAS G12D mutant (unknown origin) assessed as GDP-GTP exchange preincubated for 4 hrs followed by GppNHp and SOS1 additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed