BDBM50656377 CHEMBL6146640

SMILES CC(=O)Oc1cc(C)c2c(c1)CC[C@@](C)(CC/C=C(C)CC/C=C(C)CCC=C(C)C)O2

InChI Key InChIKey=LSPZGEMJFARJSN-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50656377   

TargetGTPase KRas(Human)
Incyte

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656377BDBM50656377(CHEMBL6146640)
Affinity DataKd:  0.160nMAssay Description:Binding affinity to KRAS G12D mutant (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
Incyte

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656377BDBM50656377(CHEMBL6146640)
Affinity DataKd:  8.80nMAssay Description:Binding affinity to wildtype KRAS (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed