BDBM50657064 CHEMBL1579974

SMILES Cc1ccc(-c2cc(C(F)F)n3ncc(C(=O)N4CCC5(CC4)OCCO5)c3n2)cc1

InChI Key InChIKey=WIXWIQYEKYWTFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657064   

TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657064BDBM50657064(CHEMBL1579974)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of TLR4 (unknown origin) homodimerizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657064BDBM50657064(CHEMBL1579974)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human TLR4 in LPS-stimulated HEK-Blue hTLR4 cells assessed as reduction in SEAP activity incubated for 24 hrs by microplate reader assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed