BDBM50657309 CHEMBL6161134

SMILES O=C(Nc1cccc(Cl)c1)c1ccccc1NS(=O)(=O)c1cccc(C(F)(F)F)c1

InChI Key InChIKey=KCGSJYWHUZKLLO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50657309   

TargetSodium-dependent organic anion transporter(Homo sapiens)
Justus Liebig University of Giessen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657309BDBM50657309(CHEMBL6161134)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of C-terminal GFP-fused human SOAT transfected in Flp-In-T-REx-HEK293 cells assessed as inhibition of [3H]DHEAS transport preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSodium/bile acid cotransporter(Human)
Justus Liebig University of Giessen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657309BDBM50657309(CHEMBL6161134)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged human NTCP transfected in Flp-In-T-REx-HEK293 cells assessed as inhibition of [3H]TC transport preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Justus Liebig University of Giessen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657309BDBM50657309(CHEMBL6161134)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal FLAG-tagged human ASBT transfected in Flp-In-T-REx-HEK293 cells assessed as inhibition of [3H]TC transport preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed