BDBM50657338 CHEMBL6103171

SMILES COc1ccc(NC(=O)Nc2nnc(Sc3ncnc4oc(-c5ccccc5)cc34)s2)cc1

InChI Key InChIKey=VPHPRDRAWMMZJP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50657338   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657338BDBM50657338(CHEMBL6103171)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant FLT3-ITD mutant expressed in baculovirus-infected Sf9 cells using AGLT (poly(Ala,Glu,Lys,Tyr)6:2:5:1 hydrobromide) as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657338BDBM50657338(CHEMBL6103171)
Affinity DataIC50: 174nMAssay Description:Inhibition of NanoLuc-fused FLT3 (unknown origin) transfected in HEK293 cells incubated for 2 hrs by NanoBRET target engagement assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657338BDBM50657338(CHEMBL6103171)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3-ITD-F691L mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed