BDBM50657422 CHEMBL6144662

SMILES Cc1ccc(CNC(=O)c2ccc(C(C)(C)C)cc2)cc1C(=O)N[C@H](C)c1cccc2ccccc12

InChI Key InChIKey=ZGTMIAQJSVSDHZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50657422   

TargetReplicase polyprotein 1ab(2019-nCoV)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657422BDBM50657422(CHEMBL6144662)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of SARS-CoV-2 PL protease using (Z)-Arg-Leu-Arg-Gly-Gly-4-methyl-coumaryl-7-amide as substrate measured every 150 sec for 1 hr by multimod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657422BDBM50657422(CHEMBL6144662)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of SARS-CoV-2 PL protease using (Z)-Arg-Leu-Arg-Gly-Gly-4-methyl-coumaryl-7-amide as substrate and varying concentration of enzyme by Line...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Institute of Science Tokyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657422BDBM50657422(CHEMBL6144662)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of SARS-CoV-2 PL protease using varying concentration of (Z)-Arg-Leu-Arg-Gly-Gly-4-methyl-coumaryl-7-amide as substrate by Dixon plot anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed