BDBM50657655 CHEMBL6147609

SMILES CCOc1ccc2cc(-c3ccc4c(c3NC(=O)NS(=O)(=O)c3cc(C(C)(C)O)co3)CCC4)ccc2c1

InChI Key InChIKey=KUJYSBHEXMEXDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50657655   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657655BDBM50657655(CHEMBL6147609)
Affinity DataIC50: 72nMAssay Description:Inhibition of NLRP3 inflammasome activation in PMA-differentiated human THP-1 cells assessed as reduction in LPS/MSU-induced IL-1beta secretion prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed