BDBM50657697 CHEMBL6132886

SMILES CCC(N)(CC)c1ccnc(Nc2cc3cc(-c4cnnn4C)nc(N)c3cn2)c1

InChI Key InChIKey=MVYWULXPOKYILU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50657697   

LigandChemical structure of BindingDB Monomer ID 50657697BDBM50657697(CHEMBL6132886)
Affinity DataKi: <0.0300nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human MASTL (1 to 879 residues) expressed in baculovirus infected Sf21 cells using AQT0693 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657697BDBM50657697(CHEMBL6132886)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MASTL in human MDA-MB-231 cells assessed as reduction in ENSA phosphorylation incubated for 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657697BDBM50657697(CHEMBL6132886)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of MASTL in human MIA PaCa-2 cells assessed as reduction in ENSA phosphorylation incubated for 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed