BDBM50657757 CHEMBL6148856

SMILES C#CC1(NC(=O)C(=O)c2c(C)c(C(=O)Nc3ccc(F)c(C#N)c3)n(C)c2C)COC1

InChI Key InChIKey=CFNQUHVMFGMRDC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50657757   

LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of OATP1B1 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier family 22 member 8(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of OAT3 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetType-1 angiotensin II receptor(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of AT1 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug and toxin extrusion protein 2(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of MATE2 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSolute carrier family 22 member 1(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of OCT1 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of OATP1B3 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMultidrug and toxin extrusion protein 1(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of MATE1 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBile salt export pump(Human)
Aligos Belgium BV

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of BSEP (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657757BDBM50657757(CHEMBL6148856)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of BCRP in human Caco-2 cells using estrone 3-sulfate as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed