BDBM50657931 CHEMBL6146311

SMILES Cc1[nH]c(/C=C2\C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccc(F)cc4)cc32)c(C)c1NC(=O)[C@H]1CCC(=O)O1

InChI Key InChIKey=AWKFMJSRWRFQIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50657931   

TargetG protein-coupled receptor kinase 6(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657931BDBM50657931(CHEMBL6146311)
Affinity DataIC50: 32nMAssay Description:Inhibition of human GRK6 expressed in Sf9 cells using porcine brain tubulin as substrate incubated for 30 secs followed by [gamma-32P]ATP addition me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetG protein-coupled receptor kinase 5(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657931BDBM50657931(CHEMBL6146311)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human GRK5 (1 to 590 residues) expressed in Escherichia coli Rosette (DE3) using porcine brain tubulin as substrate incubated for 30 se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657931BDBM50657931(CHEMBL6146311)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GRK2 using porcine brain tubulin as substrate incubated for 30 secs followed by [gamma-32P]ATP addition measured after 5 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed