BDBM50657933 CHEMBL6152245

SMILES Cc1nc2c(C(=O)Nc3c(C)[nH]c(/C=C4\C(=O)Nc5ccc(C(=O)N[C@H](C)c6ccc(F)cc6)cc54)c3C)cccc2[nH]1

InChI Key InChIKey=KOEVKQQPQGOTLN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50657933   

TargetG protein-coupled receptor kinase 6(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657933BDBM50657933(CHEMBL6152245)
Affinity DataIC50: 110nMAssay Description:Inhibition of human GRK6 expressed in Sf9 cells using porcine brain tubulin as substrate incubated for 30 secs followed by [gamma-32P]ATP addition me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetG protein-coupled receptor kinase 5(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657933BDBM50657933(CHEMBL6152245)
Affinity DataIC50: 300nMAssay Description:Inhibition of human GRK5 (1 to 590 residues) expressed in Escherichia coli Rosette (DE3) using porcine brain tubulin as substrate incubated for 30 se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBeta-adrenergic receptor kinase 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657933BDBM50657933(CHEMBL6152245)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human GRK2 using porcine brain tubulin as substrate incubated for 30 secs followed by [gamma-32P]ATP addition measured after 5 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed