BDBM50658619 CHEMBL6143486

SMILES O=[N+]([O-])c1cnc(Cl)nc1N(Cc1ccc(-c2ccc3ccccc3c2)s1)C1CCS(=O)(=O)C1

InChI Key InChIKey=DHHLYSQNWJSFRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50658619   

TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658619BDBM50658619(CHEMBL6143486)
Affinity DataIC50: 500nMAssay Description:Inhibition of human Pin1 using Suc-Ala-Glu-Pro-Phe04-nitroanilide as peptide substrate preincubated for 14 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658619BDBM50658619(CHEMBL6143486)
Affinity DataIC50: 7.75E+3nMAssay Description:Inhibition of human Pin1 extracted from Escherichia coli BL21 (DE3) cells using TAMRA labelled Bth-(D-Thr(PO3H2))-Pip-Nal-NH2 peptide probe as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed