BDBM50658687 CHEMBL6168421

SMILES CN(C)CC#Cc1ccc2[nH]nc(-c3ccnc(N)n3)c2c1

InChI Key InChIKey=GIPZDUVROJFPAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50658687   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658687BDBM50658687(CHEMBL6168421)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of PIKfyve (unknown origin) using PI(3)P:PS as substrate incubated for 60 mins in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658687BDBM50658687(CHEMBL6168421)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of PIKfyve (unknown origin) expressed in HEK293 cells using NanoBRET NanoGlo substrate in presence of K8 tracer by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed