BDBM50658805 CHEMBL6133433

SMILES CCCNNC(=O)c1ccc(Cn2c3ccccc3c3c(-c4ccccn4)nc4ccccc4c32)cc1

InChI Key InChIKey=SAWJBDKOKXSARH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50658805   

TargetHistone deacetylase 3(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant full length human HDAC6 using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 8.87E+3nMAssay Description:Inhibition of recombinant HDAC11 (unknown origin) preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence based...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 9.77E+3nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence based...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Gannan Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658805BDBM50658805(CHEMBL6133433)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed