BDBM50659084 CHEMBL6148526

SMILES C[C@H]1C(=O)N(C[C@@H](Cc2ccccc2)N(Cc2ccccc2)Cc2ccccc2)[C@@]1(Cc1ccccc1)C(=O)OCc1ccccc1

InChI Key InChIKey=GYWBPMSDZREHBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50659084   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659084BDBM50659084(CHEMBL6148526)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human recombinant TRPM8 stably transfected in HEK293 cells assessed as inhibition of intracellular Ca2+ flux incubated for 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659084BDBM50659084(CHEMBL6148526)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dalian Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659084BDBM50659084(CHEMBL6148526)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human TRPM8 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed