BDBM50659310 CHEMBL6159853

SMILES CC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnco4)c(N[C@@H](CO)c4ccccc4)n3)cc21

InChI Key InChIKey=RVSSNRBUPQUIEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50659310   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659310BDBM50659310(CHEMBL6159853)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of HPK1 (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed