BDBM50659324 CHEMBL6143211

SMILES COc1cc2c(cc1Nc1nc(Nc3ccccc3P(C)(C)=O)c3c(C#N)c[nH]c3n1)CN(C)CC2

InChI Key InChIKey=XUXVVDVPKMLJOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50659324   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659324BDBM50659324(CHEMBL6143211)
Affinity DataIC50: 47nMAssay Description:Inhibition of HPK1 (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed