BDBM50659330 CHEMBL6150635

SMILES COc1cncc(-c2cn[nH]c2/C=C/c2ccc(NC(=O)Nc3cc(C(C)(C)C(F)(F)F)on3)c(Cl)c2)c1

InChI Key InChIKey=DZFGFFOWGLWGDC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50659330   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of RET (unknown origin) G810C mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 17nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 32nMAssay Description:Inhibition of RET (unknown origin) G810R mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEphrin type-B receptor 4(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 36nMAssay Description:Inhibition of EPHB4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 63nMAssay Description:Inhibition of EPHA2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 87nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659330BDBM50659330(CHEMBL6150635)
Affinity DataIC50: 162nMAssay Description:Inhibition of RET (unknown origin) V804M mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed