BDBM50659372 CHEMBL6162858

SMILES COc1nn(C)cc1Nc1ncc2scc(-c3cccc(N)c3)c2n1

InChI Key InChIKey=RWGKWWDGUOYTOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50659372   

TargetTyrosine-protein kinase JAK1(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659372BDBM50659372(CHEMBL6162858)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK1 (438 to end residues) extracted from baculovirus infected in Sf9 cells using KKHTDDGYMPMSP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659372BDBM50659372(CHEMBL6162858)
Affinity DataIC50: 68nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK3 (781 to end residues) extracted from baculovirus infected in Sf9 cells using Poly(4:1 Glu,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Korea University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659372BDBM50659372(CHEMBL6162858)
Affinity DataIC50: 154nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant JAK2 (804 to end residues) extracted from baculovirus infected in Sf9 cells using IGF1Rtide as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed