BDBM50659749 CHEMBL6160726

SMILES Cc1cc(-c2cnn3c(-c4c(C)nn(-c5cccnc5)c4C)cc(N4CC5CCC(C4)O5)nc23)[nH]n1

InChI Key InChIKey=MDKKCGMVJYMDNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50659749   

TargetSerine/threonine-protein kinase ATR(Human)
Chinese Academy of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659749BDBM50659749(CHEMBL6160726)
Affinity DataIC50: 16nMAssay Description:Inhibition of ATR (unknown origin) assessed as reduction in p53 phosphorylation level incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed