BDBM50659888 CHEMBL6151098
SMILES O=C(O)c1ccc(-c2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CC3)cc2)cc1
InChI Key InChIKey=MUUKZGHKNDQVRC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50659888
Affinity DataEC50: 52nMAssay Description:Agonist activity at FXR-LBD (unknown origin) incubated for 3 hrs in presence of fluorescein-coactivator peptide by TR-FRET analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 132nMAssay Description:Agonist activity at FXR (unknown origin) transfected in human HepG2 cells incubated for 24 hrs by luciferase assayMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of HSD17B13 (unknown origin) using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based lum...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of FABP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RXRalpha (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter incubated...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RARalpha (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter incubated...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at RARgamma (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter incubated...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at ERalpha (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter incubated ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at LXRalpha (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter incubated...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at LXRbeta (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter incubated ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase rep...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARalpha (unknown origin) transfected in human HepG2 cells co-transfected with pBIND incubated for 18 hrs by Dual luciferase rep...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin) transfected in HEK293 cells co-transfected with pBIND incubated for 18 hrs by Dual luciferase reporter...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at ERbeta (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter incubated f...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at progesterone receptor (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase repor...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at androgen receptor (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mineralocorticoid receptor (unknown origin) transfected in green monkey CV-1 cells co-transfected with NHR responsive luciferase ...More data for this Ligand-Target Pair