BDBM50660105 CHEMBL6133781

SMILES Cc1cc2cnn(-c3cnn(C)c3)c2cc1[C@H]1C[C@@H]2CN(C3CCS(=O)(=O)CC3)C[C@@H]2C1

InChI Key InChIKey=NLHCTZMWUXFUOB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50660105   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660105BDBM50660105(CHEMBL6133781)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of wild type human LRRK2 G2019S mutant using LRRKide as substrate preincubated for 15 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660105BDBM50660105(CHEMBL6133781)
Affinity DataIC50: 79nMAssay Description:Inhibition of wild type human LRRK2 using LRRKide as substrate preincubated for 15 mins followed by substrate addition and measured after 120 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660105BDBM50660105(CHEMBL6133781)
Affinity DataIC50: 122nMAssay Description:Inhibition of wild type human LRRK2 G2019S mutant phosphorylation at S935 residue in HEK293 cells incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660105BDBM50660105(CHEMBL6133781)
Affinity DataIC50: 7.33E+3nMAssay Description:Inhibition of wild type human LRRK2 phosphorylation at S935 residue in HEK293 cells incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed