BDBM50660405 CHEMBL6173670

SMILES Nc1nc(-c2ccc(CNC(=O)Cc3ccc(NS(=O)(=O)c4ccccc4)cc3)cc2)c[nH]1

InChI Key InChIKey=SVDHOWDKPFNTMO-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50660405   

TargetMannan-binding lectin serine protease 2(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 4nMAssay Description:Inhibition of human MASP-2 (287 to 686 residues) using Z-Lys-SBzl as substrate incubated for 1 hr by plate reader based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProthrombin(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 795nMAssay Description:Inhibition of Thrombin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetUrokinase-type plasminogen activator(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine protease hepsin(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of hepsin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of Matriptase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPlasminogen(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of Plasmin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGranzyme A(Homo sapiens)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of granzyme A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of factor XIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetComplement C1s subcomponent(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of C1s (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCoagulation factor X(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor Xa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGranzyme K(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of granzyme K (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine protease 27(Homo sapiens)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of marapsin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCoagulation factor IX(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor IXa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTissue-type plasminogen activator(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of tPA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransmembrane protease serine 6(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matriptase-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetProstasin(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of prostasin (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCoagulation factor VII(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of factor VIIa (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCathepsin G(Human)
Innoviva Specialty Therapeutics, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660405BDBM50660405(CHEMBL6173670)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of cathepsin G (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed