BDBM50660430 CHEMBL6170408

SMILES O=C1C(Cl)=C(NCCc2cccc(F)c2)C(=O)c2ncccc21

InChI Key InChIKey=NIVRSGFRGILTHK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50660430   

TargetHistone-lysine N-methyltransferase NSD3(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660430BDBM50660430(CHEMBL6170408)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human NSD3 incubated for 30 mins in presence of SAM and nucleosome by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660430BDBM50660430(CHEMBL6170408)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human NSD2 incubated for 30 mins in presence of SAM and nucleosome by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50660430BDBM50660430(CHEMBL6170408)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human NSD1 incubated for 30 mins in presence of SAM and nucleosome by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed