BDBM50660628 CHEMBL6163157

SMILES Cc1cc(=O)n(-c2cc(F)ccc2F)nc1C(=O)Nc1ccc(Oc2ccnc(NC(=O)N3CC(O)C3)c2)c(F)c1

InChI Key InChIKey=XPSGMFRLHAIXFD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50660628   

TargetVascular endothelial growth factor receptor 2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660628BDBM50660628(CHEMBL6163157)
Affinity DataIC50: 131nMAssay Description:Inhibition of VEGFR2 (unknown origin) using Fluorescein-Poly GT as substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660628BDBM50660628(CHEMBL6163157)
Affinity DataIC50: 153nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using Fluorescein-Poly GT as substrate preincubated for 10 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660628BDBM50660628(CHEMBL6163157)
Affinity DataIC50: 166nMAssay Description:Inhibition of FLT4 (unknown origin) using Fluorescein-Poly GT as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660628BDBM50660628(CHEMBL6163157)
Affinity DataIC50: 348nMAssay Description:Inhibition of FLT1 (unknown origin) using Fluorescein-Poly GT as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660628BDBM50660628(CHEMBL6163157)
Affinity DataIC50: 475nMAssay Description:Inhibition of FLT3 (unknown origin) using Fluorescein-Poly GT as substrate preincubated for 10 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed