BDBM50660652 CHEMBL6161653

SMILES CC#CCn1cc(N(c2nc(C(N)=O)c(-c3cc(C(N)=O)c[nH]3)s2)C2CC2)cn1

InChI Key InChIKey=HLHJQPYTZYHCRR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50660652   

TargetTGF-beta receptor type-1(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660652BDBM50660652(CHEMBL6161653)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of ALK5 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAurora kinase C(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660652BDBM50660652(CHEMBL6161653)
Affinity DataIC50: 12nMAssay Description:Inhibition of Aurora Kinase C (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Carna Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660652BDBM50660652(CHEMBL6161653)
Affinity DataIC50: 16nMAssay Description:Inhibition of TrkC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed