BDBM50661011 CHEMBL6162114

SMILES O=c1c(NCCc2cccc(Cl)c2)c(Nc2ccc(Cl)cc2)c1=O

InChI Key InChIKey=SMNYRHJGQPPNBC-UHFFFAOYSA-N

Data  42 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 50661011   

TargetTranslocator protein(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat brain benzodiazepine receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of serotonin transporter (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of norepinephrine transporter (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine transporter (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of opioid delta receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of opioid kappa receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of opioid mu receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of muscarinic acetylcholine M5 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT1E receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT1D receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT1B receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT5A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT2B receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of sigma 2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT7A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBeta-3 adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic beta3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic beta2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic beta1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(1B) dopamine receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D5 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of histamine H4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of histamine H2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of muscarinic acetylcholine M4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of muscarinic acetylcholine M3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of muscarinic acetylcholine M2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of muscarinic acetylcholine M1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic alpha1B receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic alpha2C receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic alpha2B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic alpha2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661011BDBM50661011(CHEMBL6162114)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic alpha1D receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed