BDBM50661020 CHEMBL6149933::US20260078122, Example 33

SMILES Cc1cnc2c(-c3cccc4[nH]ncc34)c(N)c(=O)[nH]c2c1

InChI Key InChIKey=MPHFBSCPJOHTMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50661020   

LigandChemical structure of BindingDB Monomer ID 50661020BDBM50661020(CHEMBL6149933 | US20260078122, Example 33)
Affinity DataIC50: 15.9nMAssay Description:CHO-K1 cells expressing Ga16 and hGPR120 were dispensed into each well of a 96-well plate (3×104 cells/100 μl/well) and then incubated in 5% CO2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50661020BDBM50661020(CHEMBL6149933 | US20260078122, Example 33)
Affinity DataIC50: 16nMAssay Description:Inhibition of GST-tagged PKMYT1 (unknown origin) preincubated with compound for 15 mins followed by ATP addition and measured after 60 mins ADP-Glo r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661020BDBM50661020(CHEMBL6149933 | US20260078122, Example 33)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-Thrombin-tagged human WEE1 (215 to 646 end residues) incubated for 45 min in presence of ATP by ADP-Glo reag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed