BDBM50661177 CHEMBL6152345

SMILES Cc1cccc2c(C[C@@H]3NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)C(F)(F)F)C(C)(C)SSC(C)(C)[C@@H](C(=O)N[C@@H](Cc4ccc(OCCN)cc4)C(=O)N[C@@H](Cc4ccc5ccccc5c4)C(=O)NC4(C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc5cccnc5)C(=O)N(C)CC(N)=O)CCOCC4)NC(=O)[C@H](CCC(=O)N(C)C)NC3=O)c[nH]c12

InChI Key InChIKey=JBOXGAQNBQJJRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50661177   

TargetSignal transducer and activator of transcription 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661177BDBM50661177(CHEMBL6152345)
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of STAT3 phosphorylation in human PBMC cells preincubated for 30 mins followed by addition of IL-23 and measured after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetInterleukin-23 receptor(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661177BDBM50661177(CHEMBL6152345)
Affinity DataIC50: 3.20nMAssay Description:Binding affinity to Interleukin-23 receptor in HEK293 cells transfected with firefly luciferase reporter incubated for 5 hrs by luminescence based an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed