BDBM50661179 CHEMBL6167841

SMILES CC(=O)N(C)CCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3c(C)cccc23)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(=O)N(C)C)NC(=O)[C@@H](NC(=O)C(F)(F)F)C(C)(C)SSC(C)(C)[C@@H](C(=O)N[C@@H](Cc2ccc(OCCN(C)C)cc2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)NC2(C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc3cccnc3)C(=O)N(C)CC(=O)N(C)C)CCOCC2)NC1=O

InChI Key InChIKey=SSTXRDWZVNRLFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50661179   

TargetSignal transducer and activator of transcription 3(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661179BDBM50661179(CHEMBL6167841)
Affinity DataIC50: 0.00300nMAssay Description:Inhibition of STAT3 phosphorylation in human PBMC cells preincubated for 30 mins followed by addition of IL-23 and measured after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetInterleukin-23 receptor(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661179BDBM50661179(CHEMBL6167841)
Affinity DataIC50: 4.80nMAssay Description:Binding affinity to Interleukin-23 receptor in HEK293 cells transfected with firefly luciferase reporter incubated for 5 hrs by luminescence based an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed