BDBM50661224 CHEMBL6162058

SMILES NS(=O)(=O)c1ccc(/N=C2S/C(=C3C(=O)Nc4c(F)cccc43)C(=O)N2C2CC2)cc1

InChI Key InChIKey=PIDWFNMATOMHLU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50661224   

TargetCarbonic anhydrase 12(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661224BDBM50661224(CHEMBL6162058)
Affinity DataKi:  44nMAssay Description:Inhibition of recombinant human Carbonic anhydrase XII catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661224BDBM50661224(CHEMBL6162058)
Affinity DataKi:  58nMAssay Description:Inhibition of recombinant human Carbonic anhydrase IX catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hydr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661224BDBM50661224(CHEMBL6162058)
Affinity DataKi:  341nMAssay Description:Inhibition of recombinant human Carbonic anhydrase II catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hydr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661224BDBM50661224(CHEMBL6162058)
Affinity DataKi:  3.47E+3nMAssay Description:Inhibition of recombinant human Carbonic anhydrase I catalytic domain assessed as inhibition constant incubated for 15 mins by stopped-flow CO2 hydra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed