BDBM50661416 CHEMBL6150857

SMILES CC(C)c1onc(-c2ccccc2C(F)(F)F)c1COc1ccc(-c2ccc(C(=O)O)cc2)cc1

InChI Key InChIKey=YJYCHXRTTQNLRY-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50661416   

TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661416BDBM50661416(CHEMBL6150857)
Affinity DataEC50:  232nMAssay Description:Agonist activity at FXR-LBD (unknown origin) incubated for 3 hrs in presence of fluorescein-coactivator peptide by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBile acid receptor(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661416BDBM50661416(CHEMBL6150857)
Affinity DataEC50:  525nMAssay Description:Agonist activity at FXR (unknown origin) transfected in human HepG2 cells incubated for 24 hrs by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661416BDBM50661416(CHEMBL6150857)
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of HSD17B13 (unknown origin) using beta-estradiol and FAC-NAD+ as substrate incubated for 2 hrs by NAD(P)H-Glo detection reagent based lum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed