BDBM50661438 CHEMBL6163449

SMILES N#Cc1ccc(C(=O)NC2CC3(CCN(c4ccc(C#N)c(C(F)(F)F)c4)C3)C2)cc1

InChI Key InChIKey=JBKKRHRARFUUCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50661438   

TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661438BDBM50661438(CHEMBL6163449)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at wildtype androgen receptor (unknown origin) transfected in HEK293 cells co-transfected with pGL4.35 assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661438BDBM50661438(CHEMBL6163449)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at androgen receptor W742L mutant (unknown origin) transfected in HEK293 cells co-transfected with ARR2PB-pGL-basic plasmid prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAndrogen receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661438BDBM50661438(CHEMBL6163449)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at androgen receptor T878A mutant (unknown origin) transfected in HEK293 cells co-transfected with ARR2PB-pGL-basic plasmid prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed