BDBM50661895 CHEMBL6168722

SMILES CC(C)(O)c1csc(S(=O)(=O)NC(=O)Nc2c3c(cc4c2CCC4)CCC3)c1

InChI Key InChIKey=HLEOGYNUFBFPQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50661895   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661895BDBM50661895(CHEMBL6168722)
Affinity DataIC50: 270nMAssay Description:Antagonist activity against NLRP3 in PMA-primed human THP-1 cells assessed as inhibition of gramicidin-induced IL-1beta release measured after 1 hr i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed