BDBM50661898 CHEMBL6169554

SMILES CC(C)(O)c1ncc([S@](N)(=O)=NC(=O)Nc2c3c(nc4c2CCC4)CCC3)s1

InChI Key InChIKey=UQYQZNZNITURBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50661898   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661898BDBM50661898(CHEMBL6169554)
Affinity DataIC50: 340nMAssay Description:Antagonist activity against NLRP3 in PMA-primed human THP-1 cells assessed as inhibition of gramicidin-induced IL-1beta release measured after 1 hr i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
IFM Therapeutics GmbH

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661898BDBM50661898(CHEMBL6169554)
Affinity DataIC50: 520nMAssay Description:Antagonist activity against NLRP3 in human Whole blood cells assessed as inhibition of LPS-induced IL-1beta secretion pretreated for 1 hr followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed