BDBM50662029 CHEMBL305838

SMILES Cc1cc(C#N)cc(C)c1Nc1ncnc(Nc2ccc(C#N)cc2)n1

InChI Key InChIKey=SRWPURYQLUYTFE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50662029   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662029BDBM50662029(CHEMBL305838)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of HIV-1 Reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662029BDBM50662029(CHEMBL305838)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of wild type HIV-1 LAI reverse transcriptaseMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662029BDBM50662029(CHEMBL305838)
Affinity DataIC50: 32nMAssay Description:Inhibition of HIV-1 Reverse transcriptase K103N/Y181C double mutantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662029BDBM50662029(CHEMBL305838)
Affinity DataIC50: 37nMAssay Description:Inhibition of HIV-1 Reverse transcriptase L100I/K103N double mutantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed