BDBM50662031 CHEMBL6159982

SMILES Cc1cc(/C=C/C#N)cc(C)c1Nc1ncnc(Nc2ccc(C#N)cc2)n1

InChI Key InChIKey=NAJHCIGIUHEHOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50662031   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662031BDBM50662031(CHEMBL6159982)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HIV-1 Reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662031BDBM50662031(CHEMBL6159982)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of wild type HIV-1 LAI reverse transcriptaseMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662031BDBM50662031(CHEMBL6159982)
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV-1 Reverse transcriptase K103N/Y181C double mutantMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed