BDBM50662093 CHEMBL6167007

SMILES C=CC(=O)Nc1cc(N(C(=O)NCc2ccccc2)[C@H]2CC[C@H](Nc3ccc(C#N)cn3)CC2)ccc1N1CCN(C(C)C)CC1

InChI Key InChIKey=DNFVGVPSYDSTCO-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50662093   

TargetCyclin-dependent kinase 12(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK12/cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of CDK7/cyclin H/MAT1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCDK6/cyclin D1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 4.48E+3nMAssay Description:Inhibition of CDK6/cyclin D1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 4.91E+3nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-K(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of CDK9/Cyclin K (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2/Cyclin A2 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK5/p25NCK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-Y(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK14/Cyclin Y (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCDK15/Cyclin Y(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK15/Cyclin Y (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCDK3/Cyclin E(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK3/cyclin E1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 18(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK18/cyclin Y (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK5/p35NCK (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/Cyclin A2 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCDK1/Cyclin E(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/Cyclin E1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2/Cyclin E1 (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK19/Cyclin C (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-C(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 3/Cyclin-C(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK3/Cyclin C (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-Y/Cyclin-dependent kinase 16(Human)
Shanghai Institute of Organic Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK16/cyclin Y (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed